JPH0138120B2 - - Google Patents

Info

Publication number
JPH0138120B2
JPH0138120B2 JP56107178A JP10717881A JPH0138120B2 JP H0138120 B2 JPH0138120 B2 JP H0138120B2 JP 56107178 A JP56107178 A JP 56107178A JP 10717881 A JP10717881 A JP 10717881A JP H0138120 B2 JPH0138120 B2 JP H0138120B2
Authority
JP
Japan
Prior art keywords
galactopyranosyl
group
deoxy
bromide
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56107178A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5745197A (en
Inventor
Yuu Remyuu Reimondo
Marei Ratokurifu Aaru
Ei Beikaa Donarudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chembiomed Ltd
Original Assignee
Chembiomed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chembiomed Ltd filed Critical Chembiomed Ltd
Publication of JPS5745197A publication Critical patent/JPS5745197A/ja
Publication of JPH0138120B2 publication Critical patent/JPH0138120B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57469—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving tumor associated glycolinkage, i.e. TAG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP56107178A 1980-07-10 1981-07-10 O-alpha-glycoside and manufacture Granted JPS5745197A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8022656 1980-07-10

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP1022756A Division JPH01230591A (ja) 1980-07-10 1989-02-02 Ｔ―抗原決定基を有する人工抗原
JP1022757A Division JPH01230592A (ja) 1980-07-10 1989-02-02 Ｔ―抗原決定基を有する免疫吸着剤

Publications (2)

Publication Number Publication Date
JPS5745197A JPS5745197A (en) 1982-03-13
JPH0138120B2 true JPH0138120B2 (en]) 1989-08-11

Family

ID=10514682

Family Applications (4)

Application Number Title Priority Date Filing Date
JP56107178A Granted JPS5745197A (en) 1980-07-10 1981-07-10 O-alpha-glycoside and manufacture
JP62171357A Granted JPS6399091A (ja) 1980-07-10 1987-07-10 Ｏ−α−グリコシドおよびその製法
JP1022757A Granted JPH01230592A (ja) 1980-07-10 1989-02-02 Ｔ―抗原決定基を有する免疫吸着剤
JP1022756A Granted JPH01230591A (ja) 1980-07-10 1989-02-02 Ｔ―抗原決定基を有する人工抗原

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP62171357A Granted JPS6399091A (ja) 1980-07-10 1987-07-10 Ｏ−α−グリコシドおよびその製法
JP1022757A Granted JPH01230592A (ja) 1980-07-10 1989-02-02 Ｔ―抗原決定基を有する免疫吸着剤
JP1022756A Granted JPH01230591A (ja) 1980-07-10 1989-02-02 Ｔ―抗原決定基を有する人工抗原

Country Status (6)

Country Link
US (1) US4866041A (en])
EP (1) EP0044188B1 (en])
JP (4) JPS5745197A (en])
AT (1) ATE20070T1 (en])
CA (1) CA1203532A (en])
DE (1) DE3174705D1 (en])

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386026A (en) * 1981-04-20 1983-05-31 Merck & Co., Inc. Cell-specific glycopeptide ligands
AU561066B2 (en) * 1982-03-22 1987-04-30 Biocarb Ab Antibacterial composition containing an oligosaccharide
DE3220426A1 (de) * 1982-05-29 1983-12-01 Behringwerke Ag, 3550 Marburg Chemische verbindung, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der malaria
JPS58213722A (ja) * 1982-06-03 1983-12-12 Otsuka Pharmaceut Co Ltd フコ−ス抗原の製造法
JPS58211661A (ja) * 1982-06-03 1983-12-09 Otsuka Pharmaceut Co Ltd 癌関連糖鎖の測定法及び癌診断用試薬
JPS58211660A (ja) * 1982-06-03 1983-12-09 Otsuka Pharmaceut Co Ltd フコ−ス抗原を識別する抗体の製造法
US4725557A (en) * 1982-06-03 1988-02-16 Otsuka Pharmaceutical Co., Ltd. Production of fucosyl antigens and antibodies for recognizing same determination of cancer associated carbohydrate linkage using same and kit for the determination
US4629692A (en) * 1982-12-06 1986-12-16 Miles Laboratories, Inc. Immunoassay for nonenzymatically glucosylated proteins and protein fragments an index of glycemia
US4767622A (en) * 1983-08-19 1988-08-30 University Of Illinois Method and materials for development of immunological responses protective against malarial infection
JPS63264493A (ja) * 1986-12-29 1988-11-01 Mect Corp 活性カルボニル基を持つシアル酸誘導体
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
US5192661A (en) * 1987-08-04 1993-03-09 University Of Ottawa Multicomponent kit containing an antibody to a synthetic antigen of sialic acid
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5376531A (en) * 1992-09-03 1994-12-27 Northwestern University Method of detecting cancer
WO1995029927A2 (en) * 1994-05-02 1995-11-09 Biomira, Inc. Process for preparation of glycosides of tumor-associated carbohydrate antigens
GB2306400A (en) * 1995-10-27 1997-05-07 Hewlett Packard Co Micro-tooth carriage drive system for inkjet printhead
US8850964B2 (en) 2005-10-20 2014-10-07 Conagra Foods Rdm, Inc. Cooking method and apparatus
US8302528B2 (en) 2005-10-20 2012-11-06 Conagra Foods Rdm, Inc. Cooking method and apparatus
CA2527770C (en) 2005-11-21 2014-07-22 Steven M. Parsons Food tray
CA2679663C (en) 2007-03-02 2015-12-08 Catherine M. Shapiro Multi-component packaging system and apparatus
USD639656S1 (en) 2010-09-08 2011-06-14 Con Agra Foods RDM, Inc. Container lid
USD638701S1 (en) 2010-09-08 2011-05-31 Conagra Foods Rdm, Inc. Container
USD639186S1 (en) 2010-09-08 2011-06-07 Conagra Foods Rdm, Inc. Container with sleeve
USD680426S1 (en) 2012-06-12 2013-04-23 Conagra Foods Rdm, Inc. Container
CN111537315B (zh) * 2020-07-13 2020-10-02 天津德祥生物技术有限公司 红细胞膜分离液和红细胞膜分离方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1544908A (en) * 1975-07-08 1979-04-25 Chembiomed Ltd Artificial oligosaccharide antigenic determinants
GB1603609A (en) * 1977-04-14 1981-11-25 Chembiomed Ltd O-protected 2-azido-2-deoxy-glycosyl nitrates

Also Published As

Publication number Publication date
JPH01230591A (ja) 1989-09-14
EP0044188A3 (en) 1982-03-10
ATE20070T1 (de) 1986-06-15
DE3174705D1 (en) 1986-07-03
JPH0343280B2 (en]) 1991-07-01
EP0044188A2 (en) 1982-01-20
CA1203532A (en) 1986-04-22
JPS5745197A (en) 1982-03-13
JPH032873B2 (en]) 1991-01-17
JPS6399091A (ja) 1988-04-30
US4866041A (en) 1989-09-12
EP0044188B1 (en) 1986-05-28
JPH01230592A (ja) 1989-09-14
JPH0138798B2 (en]) 1989-08-16

Similar Documents

Publication Publication Date Title
JPH0138120B2 (en])
US4137401A (en) Glycoside-ether-ester compounds
CA1105011A (en) Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2- deoxyglycosides from glycals
JP3083521B2 (ja) シアル酸グリコシド，抗原，免疫吸着剤およびそれらの調整方法
US4362720A (en) Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
Allen et al. A second generation synthesis of the MBr1 (Globo‐H) breast tumor antigen: New application of the N‐pentenyl glycoside method for achieving complex carbohydrate protein linkages
Ratcliffe et al. Synthesis of the T [β-D-Gal-(1→ 3)-α-D-GalNAc]-antigenic determinant in a form useful for the preparation of an effective artificial antigen and the corresponding immunoadsorbent
US4987223A (en) Derivatives of the uronic acid
Kovac et al. Synthesis of ligands related to the O-specific antigen of type 1 Shigella dysenteriae. 3. Glycosylation of 4, 6-O-substituted derivatives of methyl 2-acetamido-2-deoxy-. alpha.-D-glucopyranoside with glycosyl donors derived from mono-and oligosaccharides.
EP0069678A2 (fr) Dérivés de 3-fucosyl-N-acétyl lactosamine, leur préparation et leurs applications biologiques
Jain et al. Synthesis of oligosaccharides containing the X-antigenic trisaccharide (α-l-Fucp-(1→ 3)-[β-d-Galp-(1→ 4)]-β-d-GlcpNAc) at their nonreducing ends
JPH09511530A (ja) 合成インスリン模倣物質
Saksena et al. Immunogens related to the synthetic tetrasaccharide side chain of the Bacillus anthracis exosporium
Aspinall et al. Synthesis of allyl glycosides for conversion into neoglycoproteins bearing epitopes of mycobacterial glycolipid antigens
Despras et al. Biotin sulfone tagged oligomannosides as immunogens for eliciting antibodies against specific mannan epitopes
Pinto et al. Synthesis of oligosaccharides corresponding to biological repeating units of Shigella flexneri variant Y polysaccharide. Part 1. Overall strategy, synthesis of a key trisaccharide intermediate, and synthesis of a pentasaccharide
US4767845A (en) Synthesis of tumor antigenic determinant
US4794176A (en) Synthesis of tumor antigenic determinant
JPH0616692A (ja) 新規糖誘導体
EP1064291B1 (en) Methods of synthesizing gm3
US5319077A (en) Process for the preparation of sugar epitopes
CA1111418A (en) Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2- deoxyglycosides from glycals
Sen et al. An Improved Method for the Synthesis of 3.6-Di-O-Methyl-D-Glucose: Preparation of the Neo-Glycoprotein Containing 3, 6-Di-O-Methyl-β-D-Glucopyranosyl-Groups
JP3026041B2 (ja) ｈＣＧ関連９糖性ハプテン
JPH0471919B2 (en])